Any technology can be learned, the question, in this case, is "by how many, in the real world?" I've been in the tuning game since the Z50 & CT70 were new new models. The number of people I've run across who really know what they're doing with carburetors has been shockingly, small. Make a big mistake with a carb and the most likely outcome is an engine that won't rev out, it either floods out or won't take throttle...change a jet, jet needle height, float level - or if one is a real expert, slide cutaway or airbleed orifice size. There aren't very many carburetor choices, for small engines. Thus, that world consists of a relatively small number of known combinations. And, carbs are largely self-adjusting, since fuel delivery depends on airflow volume of the engine. Not so with EFI, you'd better known what you're doing. A seemingly minor oversight can make paperweights. I jumped into custom EFI about 20 years ago, on the automotive side. Started out by hiring "expert" help to get a one-off setup dialed-in...by one of the premier outfits in North America. Even they didn't get it quite right...unless you consider a 70rwhp & 5mpg loss "getting it right". Took me a month to get the thing sorted...and that was equipped with a laptop on the passenger seat. Getting all of the various temp-related map values dialed-in took another 18 months. Without a temperature-controlled chamber to simulate summer vs winter ambient temps, had to wait for the real thing.
I suspect the odds are good that you will get this sorted and you won't be the only one. No insult intended but, I also believe that you're grossly overestimating the tuning skills of most people. Otherwise, I wouldn't be reading numerous posts about "light bore injector" swaps, eliminating the airbox & charcoal canister and the like, hoping for big gains from stock motors. I don't see EFI tuning becoming a viable DIY proposition, for the vast majority, until the aftermarket first steps in to do the heavy lifting...offering full-time closed-loop operation and self-mapping systems and at a price level that most will accept, while still allowing a viable profit magin (not many outfits can work for free, or at a loss). Another longshot in the "everyday waldomart low price" era.
On the automotive side, most "DIY tuners", throw money at cat-back exhausts, cold air intake assemblies and silly gauges. Notice any similarity? The majority of "hardcore tuners" purchase pre-engineered & tested packages, that include ECU remapping...or farming-out the job to a tuning shop. The DIY component involves re-mapping an ECU using a pen & checkbook.